The Anastasios G. Leventis Foundation was established in 1980 and is based in a restored neo-classical house in Gladstonos Street, Nicosia.  It is involved mainly with Cypriot projects that focus on the preservation and promotion of the island’s historical and cultural resources.

In its first 20 years, the Foundation was particularly concerned with protecting the cultural heritage of the occupied territory from looting and raiding. It purchased many important ancient Cypriot artifacts from foreign antiquities markets and donated them to the Cyprus Museum in Nicosia. It funds the preservation and restoration of key archaeological sites and historic monuments, collaborating with the Department of Antiquities of Cyprus.  Major contributions have also been made to the restoration of ecclesiastical monuments, funding the restoration of architecture and the conservation of wall paintings at many monasteries, churches and chapels.  It matches the contributions made by local communities, and this combined fund is then matched by the government.

Since 1992, it has been a major benefactor to the University of Cyprus. Having bought and restored a neoclassical house in Gladstonos Street in Nicosia, which houses the University’s Archaeological Research Unit. The University’s Senate House is name after the Foundation, in recognition of our ongoing support. A more recent donation has supported the construction of a new Biological Sciences building at the University’s campus. 

The Foundation has also been a dynamic force in the creation of new museums. It has financed the acquisition and restoration of the building which houses the Leventis Municipal Museum of Nicosia, and its subsequent organisation. As well as this, Ecclesiastical museums have been established with the Foundation's support in the Monasteries of Chryssorogiatissa and Machairas, as well as in the villages of Palaichori, Pelendri, Omodhos and Kormakiti (the latter a Maronite village in Northern Cyprus).

Support has been given to a range of environmental projects including sustainable tourism through a number of organisations including Terra Cypria, Laona Foundation and Birdlife Cyprus. 

On a more limited scale, social welfare and medical research also fall within the Foundation's domain. Since 1989 it has been one of the main supporters of the Cyprus Institute of Neurology and Genetics.  Anastasios Leventis financed the establishment of the Home for the Aged in collaboration with Archbishop Makarios II and the Foundation continues to support it and is a major contributor to the Cyprus Red Cross.